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Synergie entre deux médicaments contre la leucémie myéloïde aigüe: à un pas d’un traitement efficace

Synergie entre deux médicaments contre la leucémie myéloïde aigüe: à un pas d’un traitement efficace

En combinant deux thérapies disponibles dans le commerce, les chercheurs du LBMCC/SNU ont observé une amélioration spec...

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Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic...

Claudia Cerella A Gaigneaux A Mazumder J-y Lee E Saland Flavia Radogna T Farge F Vergez C Récher J-e Sarry ...

Published in Leukemia

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Drug synergy: one step closer to effective treatment of acute myeloid leukemia

Drug synergy: one step closer to effective treatment of acute myeloid leukemia

By combing two pre-existing therapies, researchers at the LBMCC/SNU dramatically increased their efficiency against leukemia...

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Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic...

Claudia Cerella A Gaigneaux A Mazumder J-y Lee E Saland Flavia Radogna T Farge F Vergez C Récher J-e Sarry ...

Published in Leukemia

1246 0
In cancer and aging, interconnected roles for apoptosis and cellular senescence

In cancer and aging, interconnected roles for apoptosis and cellular senescence

Researchers at the LBMCC review how these protective processes interact in cells' response to damage

A common feature of cancer and aging is cells' reduced ability to respond to stress-induced damage to DNA or cellular structu...

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Roles of Apoptosis and Cellular Senescence in Cancer and Aging

Claudia Cerella Cindy Grandjenette Mario Dicato Marc Diederich

Published in Current Topics in Medicinal Chemistry

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Steps Toward Non-Toxic Cancer Therapy, with Help From the Sea

Steps Toward Non-Toxic Cancer Therapy, with Help From the Sea

A marine sponge could provide a new tumor-blocking drug and synergies with other therapies, Luxembourg researchers find.

Plants aren’t the only natural sources of potential new cancer treatments: a sea sponge has inspired the LBMCC lab’s latest a...

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Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent induci...

Cristina Florean Michael Schnekenburger Jin-Young Lee Kyung Kim Aloran Mazumder Sungmi Song Jae-Myun Kim Cindy Grandjenette Jeoung-Gyun Kim Ah-Young Yoon ...

Published in Oncotarget

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Vers une thérapie non toxique contre le cancer, grâce à la mer

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Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent induci...

Cristina Florean Michael Schnekenburger Jin-Young Lee Kyung Kim Aloran Mazumder Sungmi Song Jae-Myun Kim Cindy Grandjenette Jeoung-Gyun Kim Ah-Young Yoon ...

Published in Oncotarget

2744 0
Reining in Aggressive Prostate Cancer: Nature Provides Two Promising Inhibitors
2263 0
De la nature au chevet du patient : des molécules naturelles prometteuses contre le cancer de la prostate agressif
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Avancées en Neuro-Oncologie : Vaincre la résistance aux traitements chez les enfants atteints du neuroblastome

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Cell type-dependent ROS and mitophagy response leads to apoptosis or necroptosis in neuroblastoma

Flavia Radogna Claudia Cerella Anthoula Gaigneaux C. Christov Mario Dicato Marc Diederich

Published in Oncogene

3670 0
Overcoming Drug Resistance in Childhood Neuroblastoma: Progress in Neuro-Oncology

Overcoming Drug Resistance in Childhood Neuroblastoma: Progress in Neuro-Oncology

A new study from Luxembourg could one day lead to personalized treatments for neuroblastoma, a notoriously drug-resistant form of cancer.

New findings from Luxembourg cancer lab LBMCC have the potential to help young children afflicted with a deadly form of cance...

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Cell type-dependent ROS and mitophagy response leads to apoptosis or necroptosis in neuroblastoma

Flavia Radogna Claudia Cerella Anthoula Gaigneaux C. Christov Mario Dicato Marc Diederich

Published in Oncogene

4505 0