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A new synthetic treatment against brain tumors may be just around the corner

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Discovery and Characterization of R/S-N-3-Cyanophenyl-N'- (6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H- 1-ben...

Michael Schnekenburger Eric Goffin Jin-Young Lee Jun Young Jang Aloran Mazumder Seungwon Ji Bernard Rogister Nafila Bouider Florence Lefranc Walter Miklos ...

Published in Journal of Medicinal Chemistry

1907 0
Des composés naturels pour développer des traitements personnalisés contre le cancer : Retour sur une année 2016 riche en découvertes avec le Pr. Diederich

Des composés naturels pour développer des traitements personnalisés contre le cancer : Retour sur une année 2016 riche en découvertes avec le Pr. Diederich

Au cours de l’année 2016, les chercheurs du LBMCC et du SNU ont identifié un éventail de composés d’origine naturelle ca...
1734 0
Synergie entre deux médicaments contre la leucémie myéloïde aigüe: à un pas d’un traitement efficace

Synergie entre deux médicaments contre la leucémie myéloïde aigüe: à un pas d’un traitement efficace

En combinant deux thérapies disponibles dans le commerce, les chercheurs du LBMCC/SNU ont observé une amélioration spec...

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Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic...

Claudia Cerella A Gaigneaux A Mazumder J-y Lee E Saland Flavia Radogna T Farge F Vergez C Récher J-e Sarry ...

Published in Leukemia

1534 0
Drug synergy: one step closer to effective treatment of acute myeloid leukemia

Drug synergy: one step closer to effective treatment of acute myeloid leukemia

By combing two pre-existing therapies, researchers at the LBMCC/SNU dramatically increased their efficiency against leukemia...

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Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic...

Claudia Cerella A Gaigneaux A Mazumder J-y Lee E Saland Flavia Radogna T Farge F Vergez C Récher J-e Sarry ...

Published in Leukemia

1618 0
In cancer and aging, interconnected roles for apoptosis and cellular senescence

In cancer and aging, interconnected roles for apoptosis and cellular senescence

Researchers at the LBMCC review how these protective processes interact in cells' response to damage

A common feature of cancer and aging is cells' reduced ability to respond to stress-induced damage to DNA or cellular structu...

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Roles of Apoptosis and Cellular Senescence in Cancer and Aging

Claudia Cerella Cindy Grandjenette Mario Dicato Marc Diederich

Published in Current Topics in Medicinal Chemistry

1421 0
Steps Toward Non-Toxic Cancer Therapy, with Help From the Sea

Steps Toward Non-Toxic Cancer Therapy, with Help From the Sea

A marine sponge could provide a new tumor-blocking drug and synergies with other therapies, Luxembourg researchers find.

Plants aren’t the only natural sources of potential new cancer treatments: a sea sponge has inspired the LBMCC lab’s latest a...

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Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent induci...

Cristina Florean Michael Schnekenburger Jin-Young Lee Kyung Kim Aloran Mazumder Sungmi Song Jae-Myun Kim Cindy Grandjenette Jeoung-Gyun Kim Ah-Young Yoon ...

Published in Oncotarget

6353 0
Vers une thérapie non toxique contre le cancer, grâce à la mer

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Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent induci...

Cristina Florean Michael Schnekenburger Jin-Young Lee Kyung Kim Aloran Mazumder Sungmi Song Jae-Myun Kim Cindy Grandjenette Jeoung-Gyun Kim Ah-Young Yoon ...

Published in Oncotarget

3072 0