Claudia Cerella Mearelli, Cristina Coppola, Simona D’alessio, Maria De Nicola, Milena Marc Diederich Ghibelli, Lina
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APOPTOSIS
The very early events of the intrinsic, damage-induced apoptotic pathway, ie, upstream to Bax activation, probably consist of physico-chemical alterations (ie, redox, pH or Ca 2+ changes) rather then subtle molecular interactions, and in spite of many studies they remain unclear. One problem is that cells undergo apoptosis in an asynchronous way, l...
Claudia Cerella Scherer, Christiane Cristofanon, Silvia Henry, Estelle Anwar, Awais Busch, Corinna Montenarh, Mathias Dicato, Mario Jacob, Claus Marc Diederich
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APOPTOSIS
Naturally occurring organic sulfur compounds (OSCs), such as linear allylsulfides from Allium species, are attracting attention in cancer research, since several OSCs were shown to act beneficially both in chemoprevention and in chemotherapy, while hardly exerting any harmful side effects. Hence, we investigated the possible role of different OSCs ...