Laboratoire de Biologie Moléculaire et Cellulaire du Cancer
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Sequential phases of Ca2+ alterations in pre-apoptotic cells

Claudia Cerella Mearelli, Cristina Coppola, Simona D’alessio, Maria De Nicola, Milena Marc Diederich Ghibelli, Lina

Published in APOPTOSIS

The very early events of the intrinsic, damage-induced apoptotic pathway, ie, upstream to Bax activation, probably consist of physico-chemical alterations (ie, redox, pH or Ca 2+ changes) rather then subtle molecular interactions, and in spite of many studies they remain unclear. One problem is that cells undergo apoptosis in an asynchronous way, l...

Cell cycle arrest in early mitosis and induction of caspase-dependent apoptosis in U937 cells by diallyltetrasulfide (Al...

Claudia Cerella Scherer, Christiane Cristofanon, Silvia Henry, Estelle Anwar, Awais Busch, Corinna Montenarh, Mathias Dicato, Mario Jacob, Claus Marc Diederich ...

Published in APOPTOSIS

Naturally occurring organic sulfur compounds (OSCs), such as linear allylsulfides from Allium species, are attracting attention in cancer research, since several OSCs were shown to act beneficially both in chemoprevention and in chemotherapy, while hardly exerting any harmful side effects. Hence, we investigated the possible role of different OSCs ...

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