Development of a matrix-assisted laser desorption/ionization–mass spectrometry screening test to evidence reversible and...
Published in Analytical Biochemistry
The cell division cycle 25 phosphatases (CDC25s) are key regulators of the physiological cell cycle progression. Their overexpression has been reported in a significant number of cancers, and their inhibition appears to be an interesting strategy for treatments. We propose here a rapid screening test allowing the detection of reversible and irrever...