Chromatin-modifying agents in anti-cancer therapy
Published in Biochimie
Epigenetic alterations are involved in every step of carcinogenesis. The development of chromatin- modifying agents (CMAs) has provided the ability to fight cancer by reversing these alterations. Currently, four CMAs have been approved for cancer treatment; two DNA demethylating agents and two deacetylase inhibitors. A number of promising CMAs are ...
