Epigenetically induced changes in nuclear textural patterns and gelatinase expression in human fibrosarcoma cells
Published in Cell Proliferation
Chromatin texture patterns of tumour cell nuclei can serve as cancer biomarkers, either to define diagnostic classifications or to obtain relevant prognostic information, in a large number of human tumours. Epigenetic mechanisms, mainly DNA methylation and histone post-translational modification, have been shown to influence chromatin packing state...
