Published in Epigenomics
Histone deacetylase (HDAC)6 is a member of the class IIb HDAC family. This enzyme is zinc-dependent and mainly localized in the cytoplasm. HDAC6 is a unique isoenzyme with two functional catalytic domains and specific physiological roles. Indeed, HDAC6 deacetylates various substrates including α-tubulin and HSP90α, and is involved in protein traffi...
Published in Epigenomics
Leukemogenesis is a multistep process in which successive transformational events enhance the ability of a clonal population arising from hematopoietic progenitor cells to proliferate, differentiate and survive. Clinically and pathologically, leukemia is subdivided into four main categories: chronic lymphocytic leukemia, chronic myeloid leukemia, a...
Published in Epigenomics
The meeting 'Cell signal-omics 2011: integrated cellular pathology - systems biology of human disease' held on 26-28 January 2011 in Luxembourg, was organized by Recherches Scientifiques Luxembourg (RSL) under the auspices of the European Research Institute for Integrated Cellular Pathology. The meeting took place in the New Conference Center Kirch...
