Localization of a regulatory region on the 5′-untranslated region of human hepatoma HepG2 γ-glutamyltransferase mRNA and...
Published in FEBS Letters
We are reporting the functional analysis of the 5'-untranslated region (5'UTR) of human hepatoma HepG2 gamma-glutamyltransferase (GGT) mRNA. Transient expression of hybrid GGT-luciferase reporter gene mutants in HepG2 shows that this 5'UTR acts as a tissue-specific translational enhancer. A domain of 173 bases containing a steroid hormone response ...