Regulation of epigenetic traits of the glutathione S-transferase P1 gene: from detoxification toward cancer prevention a...
Published in Frontiers in Pharmacology
Glutathione S-transferases (GSTs) are phase II drug detoxifying enzymes that play an essential role in the maintenance of cell integrity and protection against DNA damage by catalyzing the conjugation of glutathione to a wide variety of exo- and endogenous electrophilic substrates. Glutathione S-transferase P1 (GSTP1), the gene encoding the pi-clas...
