Schumacher, Marc Claudia Cerella Reuter, Simone Dicato, Mario Marc Diederich
Published in
Genes & Nutrition
Azadirachta indica (neem tree) is used in traditional Indian medicine for its pharmacological properties including cancer prevention and treatment. Here, we studied a neem extract's anti-inflammatory potential via the nuclear factor-κB (NF-κB) signaling pathway, linked to cancer, inflammation, and apoptosis. Cultured human leukemia cells were treat...
Barbora Orlikova Tasdemir, Deniz Golais, Frantisek Dicato, Mario Marc Diederich
Published in
Genes & Nutrition
Chalcones are absorbed in the daily diet and appear to be promising cancer chemopreventive agents. Chalcones represent an important group of the polyphenolic family, which includes a large number of naturally occurring molecules. This family possesses an interesting spectrum of biological activities, including antioxidative, antibacterial, anti-inf...
Trécul, Anne Franck Morceau Dicato, Mario Marc Diederich
Published in
Genes & Nutrition
Signal transducers and activators of transcription (STAT) proteins were described as a family of latent cytosolic transcription factors whose activation is dependent on phosphorylation via growth factor- and cytokine-membrane receptors including interferon and interleukin, or by non-receptor intracellular tyrosine kinases, including Src. A vast maj...
Francois Gaascht Dicato, Mario Marc Diederich
Published in
Genes & Nutrition
Coffee is the second most popular beverage in the world after water with a consumption of approximately two billion cups per day. Due to its low cost and ease of preparation, it is consumed in almost all countries and by all social classes of the population through different modes of preparation. Despites its simple appearance, a cup of coffee is i...
Schumacher, Marc Juncker, Tom Michael Schnekenburger Francois Gaascht Marc Diederich
Published in
Genes & Nutrition
Since 1998, Dr. Marc Diederich and his research team successfully managed eight cell signaling meetings in Luxembourg attracting more then 5,500 scientists. In January 2010, over 550 scientists and exhibitors came together for the meeting Inflammation 2010, which was held from January 27th to 30th. Invited and selected talks followed the keynote se...
Marie-Hélène Teiten Francois Gaascht Eifes, Serge Dicato, Mario Marc Diederich
Published in
Genes & Nutrition
The long latency and high incidence of prostate carcinogenesis provides the opportunity to intervene with chemoprevention in order to prevent or eradicate prostate malignancies. We present here an overview of the chemopreventive potential of curcumin (diferuloylmethane), a well-known natural compound that exhibits therapeutic promise for prostate c...
