Laboratoire de Biologie Moléculaire et Cellulaire du Cancer
  • Upload

  • Log in

  • Sign up

Search on MyScienceWork
News Publications Members Events

Publication search

Sort by
  • Relevance
  • Published Date

Protein Kinase and HDAC Inhibitors from the Endophytic Fungus Epicoccum nigrum

El Amrani, Mustapha Lai, Daowan Debbab, Abdessamad Aly, Amal H. Siems, Karsten Seidel, Carole Michael Schnekenburger Anthoula Gaigneaux Marc Diederich Feger, Daniel ...

Published in Journal of Natural Products

A chemical investigation of the endophytic fungus Epicoccum nigrum isolated from leaves of Mentha suaveolens collected in Morocco resulted in the isolation of five new polyketides, epicocconigrones A and B (1 and 2), 3-methoxyepicoccone B (3), 3-methoxyepicoccone (4), and 2,3,4-trihydroxy-6-(methoxymethyl)-5-methylbenzaldehyde (5), together with fi...

Bioactive Diterpene Derivatives from the Marine Sponge Spongionella sp.

Rateb, Mostafa E. Houssen, Wael E. Schumacher, Marc Harrison, William T. A. Marc Diederich Ebel, Rainer Jaspars, Marcel

Published in Journal of Natural Products

Three new compounds of the rare classes trisnorditerpenes, bisnorditerpenes, and norditerpenes, gracilins J-L (1, 2, 6), and a new diterpene, 3'-norspongiolactone (8), were isolated from the extract of the marine sponge Spongionella sp. using NMR- and bioassay-guided fractionation, in addition to three known gracilins (3-5) as well as the known dit...

NF-κB Inhibiting Naphthopyrones from the Fijian Echinoderm Comanthus parvicirrus

Folmer, Florence Harrison, William T. A. Tabudravu, Jioji N. Jaspars, Marcel Aalbersberg, William Feussner, Klaus Wright, Anthony D. Dicato, Mario Marc Diederich

Published in Journal of Natural Products

The two naphthopyrones 6-methoxycomaparvin (1) and 6-methoxycomaparvin 5-methyl ether (2) were isolated from a bioactive methanol-soluble extract of the Fijian echinoderm Comanthus parvicirrus. Their structures were assigned on the basis of spectroscopic methods. X-ray diffraction analysis was used to confirm the structure of 1. Both compounds were...

Powered by Polaris
  • About Us
  • Research
  • Projects
  • Meetings
  • Equipment
  • Contact
  • *Support Our Research*
  • FAQ