Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic ...
...Published in Leukemia
Leukemia accepted article preview online, 22 November 2016. doi:10.1038/leu.2016.341
Published in Leukemia
Leukemia accepted article preview online, 22 November 2016. doi:10.1038/leu.2016.341
Published in Leukemia
Induction of specific gene expression may provide an alternative or a support to conventional cytotoxic chemotherapy of cancer, as well as to therapy for sickle cell diseases. In this respect, pharmacological induction of expression of the endogenous gamma-globin gene is a realistic approach to therapy of beta-globin disorders. Erythroid differenti...