Laboratoire de Biologie Moléculaire et Cellulaire du Cancer
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Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic ...

Claudia Cerella Gaigneaux, A Mazumder, A Lee, J-y Saland, E Flavia Radogna Farge, T Vergez, F Récher, C Sarry, J-e ...

Published in Leukemia

Leukemia accepted article preview online, 22 November 2016. doi:10.1038/leu.2016.341

GTP-mediated differentiation of the human K562 cell line: transient overexpression of GATA-1 and stabilization of the γ-...

Franck Morceau Dupont, C. Palissot, V. Borde-Chiché, Patricia Trentesaux, Chantal Dicato, Mario Marc Diederich

Published in Leukemia

Induction of specific gene expression may provide an alternative or a support to conventional cytotoxic chemotherapy of cancer, as well as to therapy for sickle cell diseases. In this respect, pharmacological induction of expression of the endogenous gamma-globin gene is a realistic approach to therapy of beta-globin disorders. Erythroid differenti...

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