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Interactions of polysulfanes with components of red blood cells

Schneider, Thomas Ba, Lalla A. Khairan, Khairan Zwergel, Clemens Duc Bach, Nguyen Bernhardt, Ingolf Brandt, Wolfgang Wessjohann, Ludger Marc Diederich Jacob, Claus ...

Published in MedChemComm

Traditionally, the activity of most polysulfanes has been associated with the redox behaviour of the sulfur-sulfur bond. Here we show that polysulfanes, such as diallyltri- and tetrasulfide, also interact with cellular membranes and certain metalloproteins. Together, multiple interactions with various biological targets may explain best the biologi...

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