Characterization of caspase-dependent and caspase-independent deaths in glioblastoma cells treated with inhibitors of th...
Published in Molecular Cancer Therapeutics
The regulation of the necrotic death and its relevance in anticancer therapy are largely unknown. Here, we have investigated the proapoptotic and pronecrotic activities of two ubiquitin-proteasome system inhibitors: bortezomib and G5. The present study points out that the glioblastoma cell lines U87MG and T98G are useful models to study the suscept...
