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Oxidative Stress and Apoptosis

Cristofanon, Silvia Dicato, Mario Ghibelli, Lina Marc Diederich

Published in Redox Signaling and Regulation in Biology and Medicine

The decision of a cell to die is triggered by the imbalance between the positive signals, those needed for continuing to survive (i.e. growth factors), and negative signals (i.e. DNA damages, increased levels of oxidants) [1]. There are two major mechanisms of cell death: necrosis and apoptosis. The severity of the injury leads the cells to decide ...

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